Monkeypox is a rare virus-borne disease. It causes a rash and influenza-like symptoms. It belongs to the orthopoxvirus family, as does the more well-known virus that causes smallpox. Monkeypox was discovered in 1958 after two outbreaks of a pox-like disease in research groups of monkeys. It is primarily transmitted through human contact with infected rodents, but it can also be transmitted through skin-to-skin contact with an infected person. Monkeypox virus has two known types (clades): one that originated in Central Africa and one that originated in West Africa. The less severe West African clade is responsible for the current global outbreak (2022).
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