Viruses exhibit strong immunological responses with both cellular and humoral immunity. Cell mediated helps in governing with the help of T, B cells and Natural Killer Cells- with T cells in conjecture with MHC and humoral immunity responses basically govern by neutralizing the antigens. With the evolution of viruses and the constant mutations that they go on with, it becomes essential to understand the type of interactions it undergoes with specific antibodies. signalling directs cellular activities and coordinates cell activities. A Neutralizing antibody is also an antibody which safeguards a cell from an antigen or infectious body by inhibiting or neutralizing any effect it is biologically.